Adele Clarkson (left panel) is a senior scientist with over 20 years of experience in diagnostic immunohistochemical analytical techniques. She runs a busy diagnostic immunohistochemistry laboratory at Pathology North, Royal North Shore Hospital, a tertiary level healthcare facility which provides diagnostic services for the management of complex malignancies including haematolymphoid and solid organ neoplasms.
Adele has expertise in the optimisation of novel antibodies for research and diagnostic immunohistochemistry on formalin fixed paraffin embedded (FFPE) tissue.
The tissue micro-array resource bank (comprised of thousands of paraffin blocks spanning multiple cancer types) are created and curated by Loretta Sioson (right), our research officer. She brings with her a wealth of experience in diagnostic pathology laboratory techniques and is familar with the processing and manipulation of FFPE biospecimens, as well as familiarity with special cytochemical and immunohistochemical techniques.
Loretta uses the Veridiam tissue arrayer to create tissue micro-arrays containing 1mm diameter cores. She works with diverse tissue types, including colon, brain, thyroid, breast and lung.
Amy Sheen (right) is an experienced scientist and the group’s project manager. She mines laboratory information systems for clinical and pathological data which are used to annotate FFPE biospecimens and is responsible for the management and maintenance of our FFPE BioBank data resource.
We currently have over 17000 cases on file encompassing a range of cancer types and this number grows every year.
Amy is responsible for the management of the Human Research Ethics Committee (HREC) documentation for the group and advises on new research project ethics submissions.
Talia Fuchs (left) is a senior pathology registrar at Royal North Shore Hospital, a trainee of the Royal College of Pathologists of Australasia and a PhD candidate at the University of Sydney.
Her ongoing PhD research project is investigating the role of novel biomarkers in cancer, with particular focus on colorectal carcinoma, mesothelioma, and medullary thyroid carcinoma.
Angela Chou (right panel) is a fellow of the Royal College of Pathologists of Australasia. She divides her time between diagnostic work at Royal North Shore Hospital and cancer research.
Angela's research interest lies in the translational applications of molecular techniques in cancer diagnosis. She is also affiliated with the Australian Pancreatic Cancer Genome Initiative providing specialist input in hepatobiliaryand upper gastrointestinal pathology.
Kim George (left) is a senior administrative officer at Pathology North, Royal North Shore Hospital, with extensive experience in medical transcription and pathology data curation and mining.
Kim created the foundational datasets for the group and established processes to mine pathology information systems for data which now accompany our tissue resource.
Mahtab Farzin (right) is a fellow of the Royal College of Pathologists of Australasia. Her research interest lies in the development of potential new cancer diagnostics which can help fine-tune cancer treatment for individual patients.
Mahtab has published on the validation of novel biomarkers in pituitary and lung cancers, and is currently involved in the validation of EGFR and ALK mutation specific immunohistochemistry in lung cancer.
Shane Battye (right), trained in histopathology at the Austin, Box Hill and Peter MacCallum Cancer Hospitals after graduating from the University of Melbourne. Shane co-founded the digital pathology hub, Pathobin in 2013. His major diagnostic interests include urological and gastrointestinal pathology.
Outside of clinical work he has a passion for computer science and has been busy exploring new avenues of digital and virtual pathology. He has prototyped and patented an innovative method of slide digitisation using smartphone, robotics and 3D printed technology and lately has been developing an automated structure from motion photogrammetry system for use in 3D scanning of pathology specimens.
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